Cardinals vs Pirates Prediction and MLB Tips - 7 May 2025
Last updated: May 6, 2025, 11:45PM | Published: May 6, 2025, 1:30AM
The St. Louis Cardinals will take on the Pittsburgh Pirates in MLB action at Busch Stadium on Wednesday, starting at 9:45am AEST.
Matthew Liberatore (2-3, 3.44 ERA) will start on the mound for the Cardinals, pitting him against Paul Skenes (3-3, 2.74 ERA) for the Pirates.
This article features Stats Insider's prediction and tips for the Cardinals vs Pirates game, plus the latest betting odds in Australia.
Who Will Win?
Using trusted computer power and data, Stats Insider has simulated the outcome of Wednesday's St. Louis vs Pittsburgh MLB match-up 10,000 times.
Our proven predictive analytics model currently gives the Pirates a 52% chance of beating the Cardinals at Busch Stadium.
Cardinals vs Pirates: Odds
The current betting odds in Australia for Wednesday's MLB game at Busch Stadium are shown below:
- Head to Head: Cardinals $2.15, Pirates $1.74
- Line: Cardinals +1.5 ($1.62), Pirates -1.5 ($2.35)
- Total (Over/Under 7 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Cardinals at $2.15 and the Pirates at $1.74.
The Cardinals are 1.5-run underdogs against the Pirates, with odds of $1.62 available at TAB.
For the favourite Pirates (-1.5) to cover the line, TAB offers odds of $2.35.
The over/under for total runs scored is set at 7 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Cardinals (+1.5) are predicted to cover the line 63% of the time, while the 7-run over/under is expected to stay under 52% of the time.
Cardinals vs Pirates: Betting Tips
- Head to Head: St. Louis at $2.15 with TAB
- Line: Cardinals +1.5 at $1.62 with TAB
- Total Runs: Under 7 at $1.91 with TAB
These Cardinals vs Pirates predictions are based on detailed modelling and betting intelligence to give you the best possible advice 24/7.
While the Pirates have a higher chance of winning the game, betting on the Cardinals to win is our preferred option due to the 3.0% edge found when comparing our data-driven probabilities to the odds currently on offer.
Making use of the edges published here at Stats Insider is one of the keys to achieving long-term success as a sports bettor.
Cardinals vs Pirates: Prediction
Stats Insider provides full betting coverage of the St. Louis vs Pittsburgh game on Wednesday, including data-driven predictions and free betting tips.
Our model updates frequently, so keep checking this page for the latest betting analysis before the St. Louis vs Pittsburgh match-up.
As always, see our Best Bets for betting tips on every MLB game, as well as predictions for a wide range of other sports.
Cardinals vs Pirates: Essential Details
The match-up between the Cardinals and Pirates at Busch Stadium is scheduled to commence at 9:45am AEST on Wednesday.
- Teams: St. Louis Cardinals vs Pittsburgh Pirates
- Date: Wednesday 7 May 2025
- Time: 9:45am AEST
- Venue: Busch Stadium
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our St. Louis vs Pittsburgh predictions have been made after running 10,000 data-driven simulations of the game, carefully curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you choose to use our predictions for betting purposes, it's important to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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