Cardinals vs Pirates Prediction and MLB Tips - 7 May 2025
Last updated: May 6, 2025, 5:20PM | Published: May 6, 2025, 1:30AM
The St. Louis Cardinals will take on the Pittsburgh Pirates in MLB action at Busch Stadium on Wednesday, starting at 9:45am AEST.
The Cardinals will send Matthew Liberatore (2-3, 3.44 ERA) to the mound, while the Pirates are going with Paul Skenes (3-3, 2.74 ERA).
This article features Stats Insider's best betting tips for the Cardinals vs Pirates game, along with the latest betting odds in Australia.
Who Will Win?
Using advanced machine learning and data, Stats Insider has simulated the outcome of Wednesday's St. Louis vs Pittsburgh MLB match-up 10,000 times.
Our leading predictive analytics model gives the Pirates a 52% chance of beating the Cardinals at Busch Stadium.
Cardinals vs Pirates: Odds
The latest betting odds in Australia for Wednesday's MLB game at Busch Stadium are listed here:
- Head to Head: Cardinals $2.15, Pirates $1.74
- Line: Cardinals +1.5 ($1.62), Pirates -1.5 ($2.35)
- Total (Over/Under 7 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Cardinals at $2.15 and the Pirates at $1.74.
The Cardinals are 1.5-run underdogs against the Pirates, with odds of $1.62 available at TAB.
For the favourite Pirates (-1.5) to cover the line, TAB offers odds of $2.35.
The over/under for total runs scored is set at 7 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Cardinals (+1.5) are predicted to cover the line 63% of the time, while the 7-run over/under is expected to stay under 52% of the time.
Cardinals vs Pirates: Betting Tips
- Head to Head: St. Louis at $2.15 with TAB
- Line: Cardinals +1.5 at $1.62 with TAB
- Total Runs: Under 7 at $1.91 with TAB
When you see a 🔥, that means it's one of our best bets of the day across all sports.
These Cardinals vs Pirates predictions are based on market-leading simulations and gambling experience to give you the best possible advice every time.
While the Pirates have a higher chance of winning the game, betting on the Cardinals to win is our preferred option because of the 3.0% edge found when comparing our data-driven probabilities to the odds currently available.
Taking advantage of the edges published here at Stats Insider is pivotal to being a profitable sports bettor in the long run.
Cardinals vs Pirates: Prediction
Stats Insider provides full betting coverage of the St. Louis vs Pittsburgh game on Wednesday, including data-driven predictions and the best betting tips.
Our model updates regularly, so keep checking this page for the latest betting tips before the St. Louis vs Pittsburgh game.
As always, see Stats Insider's Best Bets for the best tips on every MLB game, plus predictions for a wide range of other sports.
Cardinals vs Pirates: Essential Details
The game between the Cardinals and Pirates at Busch Stadium is scheduled to commence at 9:45am AEST on Wednesday.
- Teams: St. Louis Cardinals vs Pittsburgh Pirates
- Date: Wednesday 7 May 2025
- Time: 9:45am AEST
- Venue: Busch Stadium
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our St. Louis vs Pittsburgh predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are accurate and reliable, so that you can make informed decisions with confidence.
If you decide to use our MLB predictions for betting purposes, it's vital that you gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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