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Cardinals vs Pirates Prediction and MLB Tips - 6 May 2025

The St. Louis Cardinals will face the Pittsburgh Pirates in MLB action at Busch Stadium on Tuesday, commencing at 9:45am AEST.

The Cardinals will send Miles Mikolas (1-2, 4.66 ERA) to the mound, while the Pirates will counter with Carmen Mlodzinski (1-3, 6.58 ERA).

This article features Stats Insider's prediction and tips for the Cardinals vs Pirates game, as well as the latest betting odds in Australia.

Who Will Win?

Utilising trusted computer power and data, Stats Insider has simulated the result of Tuesday's St. Louis vs Pittsburgh MLB match-up 10,000 times.

Our proven predictive analytics model currently gives the Cardinals a 56% chance of winning against the Pirates at Busch Stadium.

Cardinals vs Pirates: Odds

The latest betting odds in Australia for Tuesday's MLB game at Busch Stadium are listed here:

  • Head to Head: Cardinals $1.68, Pirates $2.24
  • Line: Cardinals -1.5 ($2.43), Pirates +1.5 ($1.58)
  • Total (Over/Under 8.5 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Cardinals at $1.68 and the Pirates at $2.24.

The Cardinals are 1.5-run favourites against the Pirates, with odds of $2.43 available at TAB.

For the underdog Pirates (+1.5) to cover the line, TAB offers odds of $1.58.

The over/under for total runs scored is set at 8.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Pirates (+1.5) are predicted to cover the line 63% of the time, while the 8.5-run over/under is expected to stay under 55% of the time.

Cardinals vs Pirates: Betting Tips

  • Head to Head: Pittsburgh at $2.24 with TAB
  • Line: Pirates +1.5 at $1.58 with TAB
  • Total Runs: Under 8.5 at $1.91 with TAB

Today's Cardinals vs Pirates betting tips are based on detailed modelling and gambling intelligence to give you the best possible advice every day of the year.

While the Cardinals have a higher chance of winning the game, betting on the Pirates to win is our recommended option because of the edge found when comparing our data-driven probabilities to the odds currently available.

Taking advantage of the edges published here at Stats Insider is pivotal to achieving long-term profitability.

Cardinals vs Pirates: Prediction

Stats Insider provides full coverage of the St. Louis vs Pittsburgh game on Tuesday, including data-driven predictions and live win probabilitiestips.

Remember, our model updates frequently, so refresh this page for the latest betting tips before the St. Louis vs Pittsburgh game.

As always, see our Best Bets for betting tips on every MLB game, as well as predictions for a wide range of other sports.

Cardinals vs Pirates: Essential Details

The game between the Cardinals and Pirates at Busch Stadium is scheduled to start at 9:45am AEST on Tuesday.

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our St. Louis vs Pittsburgh predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.

If you decide to use our MLB predictions for betting purposes, it's crucial that you gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures odds for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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