Cardinals vs Pirates Prediction and MLB Tips - 29 August 2025
Last updated: Aug 28, 2025, 6:15PM | Published: Aug 27, 2025, 6:30PM
The St. Louis Cardinals will face the Pittsburgh Pirates in MLB action at Busch Stadium on Friday, commencing at 4:15am AEST.
Miles Mikolas (6-10, 5.17 ERA) will get the ball for the Cardinals, up against Braxton Ashcraft (4-2, 2.70 ERA) for the Pirates.
This article features Stats Insider's prediction and tips for the Cardinals vs Pirates game, as well as the latest betting odds in Australia.
Who Will Win?
Using advanced computer power and data, Stats Insider has simulated the result of Friday's St. Louis vs Pittsburgh MLB game 10,000 times.
Our leading predictive analytics model currently gives the Cardinals a 52% chance of winning against the Pirates at Busch Stadium.
Cardinals vs Pirates: Odds
The latest betting odds in Australia for Friday's MLB game at Busch Stadium are listed here:
- Head to Head: Cardinals $1.83, Pirates $2.00
- Line: Cardinals -1.5 ($2.70), Pirates +1.5 ($1.49)
- Total (Over/Under 8 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Cardinals at $1.83 and the Pirates at $2.00.
The Cardinals are 1.5-run favourites against the Pirates, with odds of $2.70 available at TAB.
For the underdog Pirates (+1.5) to cover the line, TAB offers odds of $1.49.
The over/under for total runs scored is set at 8 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Pirates (+1.5) are predicted to cover the line 65% of the time, while the 8-run over/under is expected to go over 51% of the time.
Cardinals vs Pirates: Best Bets
- Head to Head: St. Louis at $1.83 with TAB
- Line: Pirates +1.5 at $1.49 with TAB
- Total Runs: Under 8 at $1.91 with TAB
These Cardinals vs Pirates betting tips are based on detailed modelling and betting intelligence to help you place better bets with your chosen online bookie.
Despite the Over being more likely to hit in this game, Under 8 is our best bet because of the better odds ($1.91) that are available from TAB.
Cardinals vs Pirates: Prediction
Stats Insider provides full betting coverage of the St. Louis vs Pittsburgh game on Friday, including data-driven predictions and live win probabilitiestips.
Remember, our model updates frequently, so refresh this article for the latest betting predictions before the St. Louis vs Pittsburgh match-up.
As always, see our Best Bets for the best tips for every MLB game, as well as predictions for a wide range of other sports.
Cardinals vs Pirates: Essential Details
The match-up between the Cardinals and Pirates at Busch Stadium is scheduled to commence at 4:15am AEST on Friday.
- Teams: St. Louis Cardinals vs Pittsburgh Pirates
- Date: Friday 29 August 2025
- Time: 4:15am AEST
- Venue: Busch Stadium
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our St. Louis vs Pittsburgh predictions have been made after running 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, so that you can make informed decisions with confidence.
If you choose to use our predictions for betting purposes, it's vital to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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