Cardinals vs Padres Prediction and MLB Tips - 27 July 2025
Last updated: Jul 26, 2025, 11:10PM | Published: Jul 25, 2025, 8:38PM
The St. Louis Cardinals will take on the San Diego Padres in MLB action at Busch Stadium on Sunday, commencing at 9:15am AEST.
Matthew Liberatore (6-7, 4.13 ERA) will start on the mound for the Cardinals, while the Padres will counter with Randy Vásquez (3-4, 3.73 ERA).
This article features Stats Insider's best betting tips for the Cardinals vs Padres game, plus the latest betting odds in Australia.
Who Will Win?
Utilising advanced computer power and data, Stats Insider has simulated the result of Sunday's St. Louis vs San Diego MLB match-up 10,000 times.
Our proven predictive analytics model currently gives the Cardinals a 58% chance of beating the Padres at Busch Stadium.
Cardinals vs Padres: Odds
The latest betting odds in Australia for Sunday's MLB game at Busch Stadium are listed here:
- Head to Head: Cardinals $1.67, Padres $2.25
- Line: Cardinals -1.5 ($2.29), Padres +1.5 ($1.65)
- Total (Over/Under 9 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Cardinals at $1.67 and the Padres at $2.25.
The Cardinals are listed as 1.5-run favourites against the Padres, with odds of $2.29 available at TAB.
For the underdog Padres (+1.5) to cover the line, TAB offers odds of $1.65.
The over/under for total runs scored is set at 9 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Padres (+1.5) are predicted to cover the line 60% of the time, while the 9-run over/under is expected to stay under 55% of the time.
Cardinals vs Padres: Best Bets
- Head to Head: St. Louis at $1.67 with TAB
- Line: Padres +1.5 at $1.65 with TAB
- Total Runs: Under 9 at $1.91 with TAB
Today's Cardinals vs Padres predictions are based on market-leading simulations and gambling experience to help you place smarter bets with your chosen online bookie.
Cardinals vs Padres: Prediction
Stats Insider provides full betting coverage of the St. Louis vs San Diego game on Sunday, including data-driven predictions and the best betting tips.
Our model updates regularly, so refresh this article for the latest betting analysis before the St. Louis vs San Diego match-up.
As always, see our Best Bets to get the best tips for every MLB game, as well as predictions for a wide range of other sports.
Cardinals vs Padres: Essential Details
The match-up between the Cardinals and Padres at Busch Stadium is scheduled to commence at 9:15am AEST on Sunday.
- Teams: St. Louis Cardinals vs San Diego Padres
- Date: Sunday 27 July 2025
- Time: 9:15am AEST
- Venue: Busch Stadium
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our St. Louis vs San Diego predictions have been made after running 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, so that you can make informed decisions with confidence.
If you choose to use our MLB predictions for betting purposes, it's crucial to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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