Cardinals vs Padres Prediction and MLB Tips - 26 July 2025
Last updated: Jul 25, 2025, 11:15PM | Published: Jul 24, 2025, 7:29PM
The St. Louis Cardinals will face the San Diego Padres in MLB action at Busch Stadium on Saturday, starting at 9:15am AEST.
The Cardinals will send Miles Mikolas (5-7, 5.20 ERA) to the mound, while the Padres will counter with Nick Pivetta (10-2, 2.81 ERA).
This article features Stats Insider's prediction and tips for the Cardinals vs Padres game, along with the latest betting odds in Australia.
Who Will Win?
Using trusted computer power and data, Stats Insider has simulated the outcome of Saturday's St. Louis vs San Diego MLB match-up 10,000 times.
Our leading predictive analytics model currently gives the Padres a 55% chance of defeating the Cardinals at Busch Stadium.
Cardinals vs Padres: Odds
The latest betting odds in Australia for Saturday's MLB game at Busch Stadium are listed here:
- Head to Head: Cardinals $2.15, Padres $1.74
- Line: Cardinals +1.5 ($1.62), Padres -1.5 ($2.35)
- Total (Over/Under 8.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Cardinals at $2.15 and the Padres at $1.74.
The Cardinals are listed as 1.5-run underdogs against the Padres, with odds of $1.62 available at TAB.
For the favourite Padres (-1.5) to cover the line, TAB offers odds of $2.35.
The over/under for total runs scored is set at 8.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Cardinals (+1.5) are predicted to cover the line 59% of the time, while the 8.5-run over/under is expected to stay under 51% of the time.
Cardinals vs Padres: Best Bets
- Head to Head: San Diego at $1.74 with TAB
- Line: Cardinals +1.5 at $1.62 with TAB
- Total Runs: Under 8.5 at $1.91 with TAB
Stats Insider's Cardinals vs Padres betting tips are based on world-class simulations and betting experience to help you place better bets with your chosen online bookie.
Cardinals vs Padres: Prediction
Stats Insider provides full coverage of the St. Louis vs San Diego game on Saturday, including data-driven predictions and the best betting tips.
Our model updates frequently, so keep checking this article for the latest betting predictions before the St. Louis vs San Diego match-up.
As always, see our Best Bets for betting tips on every MLB game, plus predictions for a wide range of other sports.
Cardinals vs Padres: Essential Details
The game between the Cardinals and Padres at Busch Stadium is scheduled to start at 9:15am AEST on Saturday.
- Teams: St. Louis Cardinals vs San Diego Padres
- Date: Saturday 26 July 2025
- Time: 9:15am AEST
- Venue: Busch Stadium
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our St. Louis vs San Diego predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of experienced data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, so that you can make informed decisions with confidence.
If you decide to use our MLB predictions for betting purposes, it's vital to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
More on MLB
Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, tips for every MLB game, and futures odds for the MLB.
