Cardinals vs Jaguars Prediction and Preview - NFL Week 12, 2025
Last updated: Nov 24, 2025, 1:18AM | Published: Nov 16, 2025, 5:00AM
The Arizona Cardinals will sqaure off with the Jacksonville Jaguars in NFL Week 12 action at State Farm Stadium on Monday, commencing at 8:05am AEDT.
This article features Stats Insider's free betting tips for the Cardinals vs Jaguars game, as well as the latest betting odds and touchdown scorer tips.
Who Will Win?
Using advanced machine learning and data, Stats Insider has simulated the outcome of Monday's Arizona vs Jacksonville NFL game 10,000 times.
Our leading predictive analytics model gives the Jaguars a 56% chance of beating the Cardinals at State Farm Stadium.
Cardinals vs Jaguars: Odds
The current Bet365 betting odds in Australia for Monday's NFL game at State Farm Stadium are listed here:
- Head to Head: Cardinals $2.25, Jaguars $1.67
- Line: Cardinals +2.5 ($1.91), Jaguars -2.5 ($1.91)
- Total (Over/Under 47.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Cardinals at $2.25 and the Jaguars at $1.67.
The Cardinals are listed as 2.5-point underdogs against the Jaguars, with odds of $1.91 available at Bet365.
For the favourite Jaguars (-2.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 47.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Cardinals (+2.5) are predicted to cover the line 58% of the time, while the 47.5-point over/under is expected to is considered an equal 50-50 chance of hitting.
Cardinals vs Jaguars: Betting Tips
- Head to Head: Arizona at $2.25 with Bet365
- Line: Cardinals +2.5 at $1.91 with Bet365
- Total Points: Under 47.5 at $1.91 with Bet365
When you see a 🔥, you know you've found one of our best tips of the day across any sport.
These Cardinals vs Jaguars predictions are based on market-leading simulations and gambling expertise to bring you the best possible advice around the clock.
While the Jaguars have a higher chance of winning the game, betting on the Cardinals to win is our recommended option because of the edge identified when comparing our data-driven probabilities to the odds currently on offer.
Taking advantage of the edges published on Stats Insider is crucial to achieving long-term success as a punter.
Cardinals vs Jaguars: Prediction
Stats Insider's predicted final score for Cardinals vs Jaguars at State Farm Stadium in Week 12 is the Jaguars prevailing 24-22.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full coverage of the Arizona vs Jacksonville game in Week 12, including data-driven predictions and top betting tips.
Get expert analysis from the US with Dimers' in-depth Cardinals vs Jaguars prediction.
18+. Odds correct at time of publishing and subject to change.Cardinals vs Jaguars: TD Scorer Tips
Who will score the first touchdown in Cardinals vs Jaguars? The latest data is in.
According to Stats Insider, Jacksonville's Travis Etienne is the most likely player to score the first touchdown in Cardinals vs Jaguars.
Etienne has a 10.7% chance of scoring the first TD at State Farm Stadium, while the Jaguars RB has a 51.1% chance of scoring an anytime touchdown.
Scroll down for our complete list of first touchdown scorer and anytime touchdown scorer probabilities.
First Touchdown Scorer Tips
Cardinals First TD Tips
- Trey McBride: 10.4% probability
- Bam Knight: 9.8% probability
- Michael Wilson: 5.6% probability
- Michael Carter: 5.1% probability
- Greg Dortch: 4.2% probability
Jaguars First TD Tips
- Travis Etienne: 10.7% probability
- Bhayshul Tuten: 9.3% probability
- Jakobi Meyers: 5.2% probability
- Trevor Lawrence: 5.1% probability
- Parker Washington: 4.9% probability
Anytime Touchdown Scorer Tips
Cardinals Anytime TD Tips
- Trey McBride: 46.0% probability
- Bam Knight: 44.0% probability
- Michael Wilson: 28.2% probability
- Michael Carter: 26.2% probability
- Greg Dortch: 22.1% probability
Jaguars Anytime TD Tips
- Travis Etienne: 51.1% probability
- Bhayshul Tuten: 46.3% probability
- Jakobi Meyers: 29.4% probability
- Trevor Lawrence: 28.7% probability
- Parker Washington: 28.0% probability
Cardinals-Jaguars Projected Player Stats
Of the starting quarterbacks, the Cardinals' Jacoby Brissett is projected for 248 passing yards. The Jaguars' Trevor Lawrence is expected to throw for 223 yards.
Cardinals Starting QB
- Jacoby Brissett: 248 projected passing yards
Jaguars Starting QB
- Trevor Lawrence: 223 projected passing yards
Cardinals Rushing Yards
- Bam Knight: 43 projected yards
- Michael Carter: 24 projected yards
- Jacoby Brissett: 14 projected yards
Jaguars Rushing Yards
- Travis Etienne: 59 projected yards
- Bhayshul Tuten: 39 projected yards
- Trevor Lawrence: 19 projected yards
Cardinals Receiving Yards
- Trey McBride: 75 projected yards
- Michael Wilson: 65 projected yards
- Greg Dortch: 32 projected yards
- Xavier Weaver: 19 projected yards
- Bam Knight: 16 projected yards
Jaguars Receiving Yards
- Jakobi Meyers: 50 projected yards
- Parker Washington: 45 projected yards
- Brenton Strange: 36 projected yards
- Tim Patrick: 29 projected yards
- Travis Etienne: 17 projected yards
Remember, our model updates regularly, so bookmark this article for the latest betting tips before the Arizona vs Jacksonville match-up.
As always, see our Best Bets for the best tips on every NFL game, plus predictions for a wide range of other sports.
Cardinals vs Jaguars: Week 12 Essential Details
The NFL Week 12 game between the Cardinals and Jaguars at State Farm Stadium is scheduled to begin at 8:05am AEDT on Monday.
- Teams: Arizona Cardinals vs Jacksonville Jaguars
- Date: Monday 24 November 2025
- Time: 8:05am AEDT
- Venue: State Farm Stadium
All dates and times in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.
Conclusion
Our Arizona vs Jacksonville predictions have been made based on 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use cutting-edge technology and machine learning to ensure our NFL tips are accurate and reliable, giving you the knowledge you need to make informed decisions with confidence.
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