Cardinals vs Jaguars Prediction and Preview - NFL Week 12, 2025

The Arizona Cardinals will face the Jacksonville Jaguars in NFL Week 12 action at State Farm Stadium on Monday, commencing at 8:05am AEDT.

This article features Stats Insider's free betting tips for the Cardinals vs Jaguars game, as well as the latest betting odds in Australia.

Who Will Win?

Using advanced computer power and data, Stats Insider has simulated the result of Monday's Arizona vs Jacksonville NFL match-up 10,000 times.

Our leading predictive analytics model currently gives the Cardinals a 58% chance of winning against the Jaguars in Week 12 of the NFL season.

Cardinals vs Jaguars: Odds

The latest Bet365 betting odds in Australia for Monday's NFL game at State Farm Stadium are listed below:

• Head to Head: Cardinals $2.25, Jaguars $1.67
• Line: Cardinals +2.5 ($1.91), Jaguars -2.5 ($1.91)
• Total (Over/Under 47.5 Points): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, Bet365 currently has the Cardinals at $2.25 and the Jaguars at $1.67.

The Cardinals are 2.5-point underdogs against the Jaguars, with odds of $1.91 available at Bet365.

For the favourite Jaguars (-2.5) to cover the line, Bet365 offers odds of $1.91.

The over/under for total points scored is set at 47.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the Cardinals (+2.5) are predicted to cover the line 66% of the time, while the 47.5-point over/under is expected to stay under 54% of the time.

Cardinals vs Jaguars: Best Bets

• Head to Head: Arizona at $2.25 with Bet365
• Line: Cardinals +2.5 at $1.91 with Bet365
• Total Points: Under 47.5 at $1.91 with Bet365

When you see a 🔥, you know you've found one of our best tips of the day across all sports.

Stats Insider's Cardinals vs Jaguars betting tips are based on detailed modelling and gambling experience to help you place better bets with your chosen online bookie.

Cardinals vs Jaguars: Prediction

Stats Insider's predicted final score for Cardinals vs Jaguars at State Farm Stadium in Week 12 is the Cardinals winning 24-22.

This prediction is based on each team's average score from 10,000 game simulations.

Stats Insider provides full betting coverage of the Arizona vs Jacksonville game in Week 12, including data-driven predictions and live scorestips.

Our model updates regularly, so bookmark this page for the latest betting tips before the Arizona vs Jacksonville game.

As always, see our Best Bets to get betting tips on every NFL game, plus predictions for a wide range of other sports.

Cardinals vs Jaguars: Week 12 Essential Details

The NFL Week 12 match-up between the Cardinals and Jaguars at State Farm Stadium is scheduled to commence at 8:05am AEDT on Monday.

• Teams: Arizona Cardinals vs Jacksonville Jaguars
• Date: Monday 24 November 2025
• Time: 8:05am AEDT
• Venue: State Farm Stadium

All dates and times mentioned in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.

Conclusion

Our Arizona vs Jacksonville predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our NFL tips are accurate and reliable, so that you can make informed decisions with confidence.

If you decide to use our predictions for betting purposes, it's vital to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

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