Cardinals vs Falcons Prediction and Preview - NFL Week 16, 2025
Last updated: Dec 21, 2025, 9:00PM | Published: Dec 14, 2025, 5:05AM
The Arizona Cardinals will face the Atlanta Falcons in NFL Week 16 action at State Farm Stadium on Monday, starting at 8:05am AEDT.
This article features Stats Insider's prediction and tips for the Cardinals vs Falcons game, as well as the latest betting odds and touchdown scorer tips.
Who Will Win?
Based on advanced computer power and data, Stats Insider has simulated the outcome of Monday's Arizona vs Atlanta NFL game 10,000 times.
Our proven predictive analytics model gives the Falcons a 56% chance of winning against the Cardinals at State Farm Stadium.
Cardinals vs Falcons: Odds
The current Bet365 betting odds in Australia for Monday's NFL game at State Farm Stadium are shown below:
- Head to Head: Cardinals $2.25, Falcons $1.67
- Line: Cardinals +2.5 ($1.91), Falcons -2.5 ($1.91)
- Total (Over/Under 48.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Cardinals at $2.25 and the Falcons at $1.67.
The Cardinals are 2.5-point underdogs against the Falcons, with odds of $1.91 available at Bet365.
For the favourite Falcons (-2.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 48.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Cardinals (+2.5) are predicted to cover the line 58% of the time, while the 48.5-point over/under is expected to is considered an equal 50-50 chance of hitting.
Cardinals vs Falcons: Best Bets
- Head to Head: Arizona at $2.25 with Bet365
- Line: Cardinals +2.5 at $1.91 with Bet365
- Total Points: Under 48.5 at $1.91 with Bet365
If you see a 🔥, that means you've found one of Stats Insider's best tips for today across any sport.
Today's Cardinals vs Falcons betting tips are based on world-class simulations and gambling experience to give you the best possible advice around the clock.
While the Falcons have a higher chance of winning the game, betting on the Cardinals to win is our recommended option because of the edge found when comparing our data-led probabilities to the odds currently available.
Making use of the edges published here at Stats Insider is one of the keys to achieving long-term success as a sports bettor.
Cardinals vs Falcons: Prediction
Stats Insider's predicted final score for Cardinals vs Falcons at State Farm Stadium in Week 16 is the Falcons winning 24-23.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full coverage of the Arizona vs Atlanta game in Week 16, including data-driven predictions and live scorestips.
For in-depth analysis from US experts,, check out Dimers' detailed Cardinals vs Falcons prediction.
18+. Odds correct at time of publishing and subject to change.Cardinals vs Falcons: TD Scorer Tips
Who will score an anytime touchdown in Cardinals vs Falcons? The data is in.
According to Stats Insider, Atlanta's Bijan Robinson is the most likely player to score the first touchdown in Cardinals vs Falcons.
Robinson has a 15.7% chance of scoring the first TD at State Farm Stadium, while the Falcons RB has a 58.4% chance of scoring an anytime touchdown.
Scroll down for our full list of first touchdown scorer and anytime touchdown scorer probabilities.
First Touchdown Scorer Tips
Cardinals First TD Tips
- Trey McBride: 9.6% probability
- Michael Carter: 7.6% probability
- Michael Wilson: 7.5% probability
- Marvin Harrison: 6.2% probability
- Emari Demercado: 3.6% probability
Falcons First TD Tips
- Bijan Robinson: 15.7% probability
- Drake London: 9.3% probability
- Tyler Allgeier: 8.6% probability
- Kyle Pitts: 7.1% probability
- Darnell Mooney: 3.8% probability
Anytime Touchdown Scorer Tips
Cardinals Anytime TD Tips
- Trey McBride: 42.1% probability
- Michael Carter: 35.1% probability
- Michael Wilson: 34.5% probability
- Marvin Harrison: 29.6% probability
- Emari Demercado: 18.6% probability
Falcons Anytime TD Tips
- Bijan Robinson: 58.4% probability
- Drake London: 40.6% probability
- Tyler Allgeier: 38.3% probability
- Kyle Pitts: 32.7% probability
- Darnell Mooney: 18.9% probability
Cardinals-Falcons Projected Player Stats
Of the starting quarterbacks, the Cardinals' Jacoby Brissett is projected for 260 passing yards, while the Falcons' Kirk Cousins is expected to throw for 233 yards.
Cardinals Starting QB
- Jacoby Brissett: 260 projected passing yards
Falcons Starting QB
- Kirk Cousins: 233 projected passing yards
Cardinals Rushing Yards
- Michael Carter: 52 projected yards
- Emari Demercado: 22 projected yards
- Jacoby Brissett: 15 projected yards
Falcons Rushing Yards
- Bijan Robinson: 97 projected yards
- Tyler Allgeier: 35 projected yards
- Kirk Cousins: 2 projected yards
Cardinals Receiving Yards
- Trey McBride: 71 projected yards
- Michael Wilson: 62 projected yards
- Marvin Harrison: 52 projected yards
- Michael Carter: 23 projected yards
- Jalen Brooks: 18 projected yards
Falcons Receiving Yards
- Drake London: 72 projected yards
- Kyle Pitts: 55 projected yards
- Bijan Robinson: 39 projected yards
- Darnell Mooney: 32 projected yards
- David Sills: 21 projected yards
Our model updates frequently, so refresh this page for the latest betting tips before the Arizona vs Atlanta game.
As always, see Stats Insider's Best Bets to get betting tips for every NFL game, plus predictions for a wide range of other sports.
Cardinals vs Falcons: Week 16 Essential Details
The NFL Week 16 match-up between the Cardinals and Falcons at State Farm Stadium is scheduled to start at 8:05am AEDT on Monday.
- Teams: Arizona Cardinals vs Atlanta Falcons
- Date: Monday 22 December 2025
- Time: 8:05am AEDT
- Venue: State Farm Stadium
All dates and times mentioned in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.
Conclusion
Our Arizona vs Atlanta predictions have been made thanks to 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use cutting-edge technology and machine learning to ensure our NFL tips are accurate and reliable, giving you the confidence to make informed decisions.
If you decide to use our predictions for betting purposes, it's crucial to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
More on NFL
Stats Insider is your go-to source for betting on the NFL in Australia, with the latest NFL betting news, predictions for every NFL game, and Super Bowl odds for the NFL.
