Cardinals vs Cubs Prediction and MLB Tips - 31 July 2026

The St. Louis Cardinals will face the Chicago Cubs in MLB action at Busch Stadium on Friday, starting at 4:15am AEST.

Andre Pallante (11-6, 3.77 ERA) will start for the Cardinals, while the Cubs are going with Javier Assad (6-1, 3.86 ERA).

This article features Stats Insider's prediction and tips for the Cardinals vs Cubs game, along with the latest betting odds in Australia.

Who Will Win?

Utilising advanced computer power and data, Stats Insider has simulated the outcome of Friday's St. Louis vs Cubs MLB game 10,000 times.

Our independent predictive analytics model gives the Cardinals a 52% chance of defeating the Cubs at Busch Stadium.

Cardinals vs Cubs: Odds

The current betting odds in Australia for Friday's MLB game at Busch Stadium are shown here:

• Head to Head: Cardinals $1.83, Cubs $2.00
• Line: Cardinals +1.5 ($1.50), Cubs -1.5 ($2.65)
• Total (Over/Under 8.5 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Cardinals at $1.83 and the Cubs at $2.00.

The Cardinals are listed as 1.5-run underdogs against the Cubs, with odds of $1.50 available at TAB.

For the favourite Cubs (-1.5) to cover the line, TAB offers odds of $2.65.

The over/under for total runs scored is set at 8.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the Cardinals (+1.5) are predicted to cover the line 64% of the time, while the 8.5-run over/under is expected to go over 53% of the time.

Cardinals vs Cubs: Best Bets

• Head to Head: Cubs at $2.00 with TAB
• Line: Cubs -1.5 at $2.65 with TAB
• Total Runs: Over 8.5 at $1.91 with TAB

Stats Insider's Cardinals vs Cubs best bets are based on market-leading modelling and wagering expertise to give you the best possible advice 24/7.

And while the Cardinals have a higher chance of winning the game, betting on the Cubs to win is our recommended option because of the edge identified when comparing our data-led probabilities to the odds currently on offer.

Making use of the edges seen here at Stats Insider is one of the keys to being profitable in the long run.

Even though the Cardinals are more likely to cover the line, our best bet of Cubs -1.5 is based on the probability of that happening, as projected by our predictive analytics model, and the best odds available.

Cardinals vs Cubs: Prediction

Stats Insider provides full coverage of the St. Louis vs Cubs game on Friday, including data-driven predictions and free betting tips.

Remember, our model updates frequently, so keep checking this page for the latest betting analysis before the St. Louis vs Cubs game.

As always, see our Best Bets to get the best tips for every MLB game, plus predictions for a wide range of other sports.

Cardinals vs Cubs: Essential Details

The match-up between the Cardinals and Cubs at Busch Stadium is scheduled to begin at 4:15am AEST on Friday.

• Teams: St. Louis Cardinals vs Chicago Cubs
• Date: Friday 31 July 2026
• Time: 4:15am AEST
• Venue: Busch Stadium

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our St. Louis vs Cubs predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.

If you choose to use our MLB predictions for betting purposes, it's crucial that you gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

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