Cardinals vs Cubs Prediction and MLB Tips - 28 July 2026
Last updated: Jul 28, 2026, 1:32AM | Published: Jul 27, 2026, 12:31AM
The St. Louis Cardinals will face the Chicago Cubs in MLB action at Busch Stadium on Tuesday, commencing at 9:45am AEST.
The Cardinals will have Matthew Liberatore (5-7, 5.18 ERA) start, pitting him against David Peterson (5-7, 5.97 ERA) for the Cubs.
This article features Stats Insider's prediction and tips for the Cardinals vs Cubs game, as well as the latest betting odds in Australia.
Who Will Win?
Using advanced computer power and data, Stats Insider has simulated the result of Tuesday's St. Louis vs Cubs MLB match-up 10,000 times.
Our leading predictive analytics model currently gives the Cubs a 53% chance of defeating the Cardinals at Busch Stadium.
Cardinals vs Cubs: Odds
The current betting odds in Australia for Tuesday's MLB game at Busch Stadium are shown here:
- Head to Head: Cardinals $2.00, Cubs $1.83
- Line: Cardinals +1.5 ($1.67), Cubs -1.5 ($2.25)
- Total (Over/Under 9.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Cardinals at $2.00 and the Cubs at $1.83.
The Cardinals are 1.5-run underdogs against the Cubs, with odds of $1.67 available at TAB.
For the favourite Cubs (-1.5) to cover the line, TAB offers odds of $2.25.
The over/under for total runs scored is set at 9.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Cardinals (+1.5) are predicted to cover the line 57% of the time, while the 9.5-run over/under is expected to go over 51% of the time.
Cardinals vs Cubs: Best Bets
- Head to Head: Cubs at $1.83 with TAB
- Line: Cubs -1.5 at $2.25 with TAB
- Total Runs: Over 9.5 at $1.91 with TAB
Today's Cardinals vs Cubs best bets are based on market-leading simulations and gambling expertise to help you place more informed bets with your chosen online bookie.
Although the Cardinals are more likely to cover the line, our best bet of Cubs -1.5 is based on the chance of that happening, as projected by our predictive analytics model, and the best odds available.
Cardinals vs Cubs: Prediction
Stats Insider provides full coverage of the St. Louis vs Cubs game on Tuesday, including data-driven predictions and live win probabilitiestips.
Our model updates frequently, so keep checking this page for the latest betting predictions before the St. Louis vs Cubs game.
As always, see Stats Insider's Best Bets to get the best tips for every MLB game, as well as predictions for a wide range of other sports.
Cardinals vs Cubs: Essential Details
The game between the Cardinals and Cubs at Busch Stadium is scheduled to commence at 9:45am AEST on Tuesday.
- Teams: St. Louis Cardinals vs Chicago Cubs
- Date: Tuesday 28 July 2026
- Time: 9:45am AEST
- Venue: Busch Stadium
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our St. Louis vs Cubs predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the knowledge you need to make informed decisions with confidence.
If you choose to use our MLB predictions for betting purposes, it's vital to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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