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Cardinals vs Cubs Prediction and MLB Tips - 26 June 2025

The St. Louis Cardinals will face the Chicago Cubs in MLB action at Busch Stadium on Thursday, starting at 9:45am AEST.

The Cardinals will have Erick Fedde (3-6, 3.54 ERA) start, while the Cubs are going with Matthew Boyd (6-3, 2.84 ERA).

This article features Stats Insider's free betting tips for the Cardinals vs Cubs game, as well as the latest betting odds in Australia.

Who Will Win?

Utilising advanced machine learning and data, Stats Insider has simulated the result of Thursday's St. Louis vs Cubs MLB match-up 10,000 times.

Our proven predictive analytics model gives the Cubs a 57% chance of winning against the Cardinals at Busch Stadium.

Cardinals vs Cubs: Odds

The current betting odds in Australia for Thursday's MLB game at Busch Stadium are shown here:

  • Head to Head: Cardinals $2.35, Cubs $1.62
  • Line: Cardinals +1.5 ($1.80), Cubs -1.5 ($2.04)
  • Total (Over/Under 9 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Cardinals at $2.35 and the Cubs at $1.62.

The Cardinals are 1.5-run underdogs against the Cubs, with odds of $1.80 available at TAB.

For the favourite Cubs (-1.5) to cover the line, TAB offers odds of $2.04.

The over/under for total runs scored is set at 9 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's model, the Cardinals (+1.5) are predicted to cover the line 56% of the time, while the 9-run over/under is expected to stay under 58% of the time.

Cardinals vs Cubs: Best Bets

  • Head to Head: St. Louis at $2.35 with TAB
  • Line: Cardinals +1.5 at $1.80 with TAB
  • Total Runs: Under 9 at $1.91 with TAB

Our Cardinals vs Cubs betting tips are based on detailed modelling and wagering expertise to provide you with the best possible advice 24/7.

While the Cubs have a higher chance of winning the game, betting on the Cardinals to win is our preferred option due to the 2.2% edge found when comparing our data-driven probabilities to the odds currently on offer.

Taking advantage of the edges seen on Stats Insider is pivotal to being profitable in the long run.

Cardinals vs Cubs: Prediction

Stats Insider provides full betting coverage of the St. Louis vs Cubs game on Thursday, including data-driven predictions and the best betting tips.

Our model updates frequently, so keep checking this article for the latest betting tips before the St. Louis vs Cubs game.

As always, see our Best Bets for betting tips for every MLB game, plus predictions for a wide range of other sports.

Cardinals vs Cubs: Essential Details

The game between the Cardinals and Cubs at Busch Stadium is scheduled to commence at 9:45am AEST on Thursday.

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our St. Louis vs Cubs predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.

If you choose to use our predictions for betting purposes, it's vital to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, tips for every MLB game, and futures odds for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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