Cardinals vs Cubs Prediction and MLB Tips - 25 June 2025
Last updated: Jun 24, 2025, 11:45PM | Published: Jun 23, 2025, 11:29PM
The St. Louis Cardinals will take on the Chicago Cubs in MLB action at Busch Stadium on Wednesday, commencing at 9:45am AEST.
Michael McGreevy (1-1, 2.70 ERA) will start on the mound for the Cardinals, while the Cubs are going with Jameson Taillon (7-4, 3.84 ERA).
This article features Stats Insider's free betting tips for the Cardinals vs Cubs game, along with the latest betting odds in Australia.
Who Will Win?
Utilising trusted computer power and data, Stats Insider has simulated the result of Wednesday's St. Louis vs Cubs MLB game 10,000 times.
Our independent predictive analytics model is unable to split the two teams, giving both the Cardinals and the Cubs an equal 50% chance of winning the game.
Cardinals vs Cubs: Odds
The latest betting odds in Australia for Wednesday's MLB game at Busch Stadium are shown below:
- Head to Head: Cardinals $1.95, Cubs $1.87
- Line: Cardinals +1.5 ($1.59), Cubs -1.5 ($2.45)
- Total (Over/Under 8.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Cardinals at $1.95 and the Cubs at $1.87.
The Cardinals are listed as 1.5-run underdogs against the Cubs, with odds of $1.59 available at TAB.
For the favourite Cubs (-1.5) to cover the line, TAB offers odds of $2.45.
The over/under for total runs scored is set at 8.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Cardinals (+1.5) are predicted to cover the line 63% of the time, while the 8.5-run over/under is expected to is considered an equal 50-50 chance of hitting.
Cardinals vs Cubs: Betting Tips
- Head to Head: St. Louis at $1.95 with TAB
- Line: Cardinals +1.5 at $1.59 with TAB
- Total Runs: Under 8.5 at $1.91 with TAB
Today's Cardinals vs Cubs best bets are based on detailed simulations and gambling intelligence to bring you the best possible advice 24/7.
Cardinals vs Cubs: Prediction
Stats Insider provides full coverage of the St. Louis vs Cubs game on Wednesday, including data-driven predictions and live updatestips.
Remember, our model updates regularly, so refresh this article for the latest betting tips before the St. Louis vs Cubs match-up.
As always, see our Best Bets for betting tips on every MLB game, plus predictions for a wide range of other sports.
Cardinals vs Cubs: Essential Details
The match-up between the Cardinals and Cubs at Busch Stadium is scheduled to begin at 9:45am AEST on Wednesday.
- Teams: St. Louis Cardinals vs Chicago Cubs
- Date: Wednesday 25 June 2025
- Time: 9:45am AEST
- Venue: Busch Stadium
All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our St. Louis vs Cubs predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the confidence to make informed decisions.
If you decide to use our predictions for betting purposes, it's vital to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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