Cardinals vs Brewers Prediction and MLB Tips - 20 September 2025
Last updated: Sep 19, 2025, 1:57PM | Published: Sep 18, 2025, 7:31PM
The St. Louis Cardinals will take on the Milwaukee Brewers in MLB action at Busch Stadium on Saturday, commencing at 10:15am AEST.
Sonny Gray (13-8, 4.43 ERA) will start on the mound for the Cardinals, pitting him against Jacob Misiorowski (5-2, 4.35 ERA) for the Brewers.
This article features Stats Insider's top betting tips for the Cardinals vs Brewers game, along with the latest betting odds in Australia.
Who Will Win?
Based on advanced machine learning and data, Stats Insider has simulated the result of Saturday's St. Louis vs Milwaukee MLB match-up 10,000 times.
Our leading predictive analytics model is currently unable to split the two teams, giving both the Cardinals and the Brewers an equal 50% chance of winning the game.
Cardinals vs Brewers: Odds
The latest betting odds in Australia for Saturday's MLB game at Busch Stadium are listed here:
- Head to Head: Cardinals $2.00, Brewers $1.83
- Line: Cardinals +1.5 ($1.59), Brewers -1.5 ($2.45)
- Total (Over/Under 7.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Cardinals at $2.00 and the Brewers at $1.83.
The Cardinals are listed as 1.5-run underdogs against the Brewers, with odds of $1.59 available at TAB.
For the favourite Brewers (-1.5) to cover the line, TAB offers odds of $2.45.
The over/under for total runs scored is set at 7.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Cardinals (+1.5) are predicted to cover the line 63% of the time, while the 7.5-run over/under is expected to go over 53% of the time.
Cardinals vs Brewers: Betting Tips
- Head to Head: St. Louis at $2.00 with TAB
- Line: Cardinals +1.5 at $1.59 with TAB
- Total Runs: Over 7.5 at $1.91 with TAB
Today's Cardinals vs Brewers best bets are based on detailed modelling and betting experience to provide you with the best possible advice around the clock.
Cardinals vs Brewers: Prediction
Stats Insider provides full betting coverage of the St. Louis vs Milwaukee game on Saturday, including data-driven predictions and expert tips.
Our model updates frequently, so keep checking this page for the latest betting analysis before the St. Louis vs Milwaukee game.
As always, see Stats Insider's Best Bets to get betting tips for every MLB game, as well as predictions for a wide range of other sports.
Cardinals vs Brewers: Essential Details
The match-up between the Cardinals and Brewers at Busch Stadium is scheduled to begin at 10:15am AEST on Saturday.
- Teams: St. Louis Cardinals vs Milwaukee Brewers
- Date: Saturday 20 September 2025
- Time: 10:15am AEST
- Venue: Busch Stadium
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our St. Louis vs Milwaukee predictions have been made thanks to 10,000 data-driven simulations of the game, carefully curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are accurate and reliable, so that you can make informed decisions with confidence.
If you decide to use our predictions for betting purposes, it's important that you gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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