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Brewers vs Orioles Prediction and MLB Tips - 21 May 2025

The Milwaukee Brewers will face the Baltimore Orioles in MLB action at American Family Field on Wednesday, commencing at 9:40am AEST.

The Brewers will send Logan Henderson (2-0, 2.46 ERA) to the mound, while the Orioles are going with Keegan Akin (0-0, 3.27 ERA).

This article features Stats Insider's free betting tips for the Brewers vs Orioles game, plus the latest betting odds in Australia.

Who Will Win?

Based on advanced machine learning and data, Stats Insider has simulated the outcome of Wednesday's Milwaukee vs Baltimore MLB game 10,000 times.

Our leading predictive analytics model currently gives the Brewers a 51% chance of beating the Orioles at American Family Field.

Brewers vs Orioles: Odds

The current betting odds in Australia for Wednesday's MLB game at American Family Field are shown below:

  • Head to Head: Brewers $1.80, Orioles $2.05
  • Line: Brewers -1.5 ($2.65), Orioles +1.5 ($1.50)
  • Total (Over/Under 8.5 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Brewers at $1.80 and the Orioles at $2.05.

The Brewers are 1.5-run favourites against the Orioles, with odds of $2.65 available at TAB.

For the underdog Orioles (+1.5) to cover the line, TAB offers odds of $1.50.

The over/under for total runs scored is set at 8.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Orioles (+1.5) are predicted to cover the line 67% of the time, while the 8.5-run over/under is expected to stay under 53% of the time.

Brewers vs Orioles: Best Bets

  • Head to Head: Baltimore at $2.05 with TAB
  • Line: Orioles +1.5 at $1.50 with TAB
  • Total Runs: Under 8.5 at $1.91 with TAB

These Brewers vs Orioles best bets are based on complex simulations and gambling experience to help you place better bets with your chosen online bookie.

While the Brewers have a higher chance of winning the game, betting on the Orioles to win is our recommended option due to the 2.5% edge identified when comparing our data-led probabilities to the odds currently on offer.

Taking advantage of the edges seen on Stats Insider is crucial to being a profitable sports bettor in the long run.

Brewers vs Orioles: Prediction

Stats Insider provides full betting coverage of the Milwaukee vs Baltimore game on Wednesday, including data-driven predictions and live win probabilitiestips.

Our model updates frequently, so refresh this article for the latest betting tips before the Milwaukee vs Baltimore game.

As always, see our Best Bets to get the best tips on every MLB game, plus predictions for a wide range of other sports.

Brewers vs Orioles: Essential Details

The game between the Brewers and Orioles at American Family Field is scheduled to begin at 9:40am AEST on Wednesday.

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our Milwaukee vs Baltimore predictions are based on 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the knowledge you need to make informed decisions with confidence.

If you decide to use our predictions for betting purposes, it's crucial that you gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures probabilities for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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