Brewers vs Cardinals Prediction and MLB Tips - 15 September 2025
Last updated: Sep 14, 2025, 6:11PM | Published: Sep 13, 2025, 7:32PM
The Milwaukee Brewers will face the St. Louis Cardinals in MLB action at American Family Field on Monday, starting at 4:10am AEST.
The Brewers will send Jose Quintana (11-6, 3.88 ERA) to the mound, while the Cardinals will counter with Miles Mikolas (7-10, 4.84 ERA).
This article features Stats Insider's best betting tips for the Brewers vs Cardinals game, plus the latest betting odds in Australia.
Who Will Win?
Using trusted computer power and data, Stats Insider has simulated the outcome of Monday's Milwaukee vs St. Louis MLB game 10,000 times.
Our independent predictive analytics model currently gives the Brewers a 64% chance of defeating the Cardinals at American Family Field.
Brewers vs Cardinals: Odds
The latest betting odds in Australia for Monday's MLB game at American Family Field are shown here:
- Head to Head: Brewers $1.50, Cardinals $2.65
- Line: Brewers -1.5 ($2.04), Cardinals +1.5 ($1.80)
- Total (Over/Under 8.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Brewers at $1.50 and the Cardinals at $2.65.
The Brewers are 1.5-run favourites against the Cardinals, with odds of $2.04 available at TAB.
For the underdog Cardinals (+1.5) to cover the line, TAB offers odds of $1.80.
The over/under for total runs scored is set at 8.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Cardinals (+1.5) are predicted to cover the line 54% of the time, while the 8.5-run over/under is expected to go over 52% of the time.
Brewers vs Cardinals: Best Bets
- Head to Head: Milwaukee at $1.50 with TAB
- Line: Cardinals +1.5 at $1.80 with TAB
- Total Runs: Under 8.5 at $1.91 with TAB
Stats Insider's Brewers vs Cardinals betting tips are based on complex simulations and betting experience to provide you with the best possible advice around the clock.
Despite the Over being more likely to hit in this game, Under 8.5 is our best bet because of the better odds ($1.91) that are available from TAB.
Brewers vs Cardinals: Prediction
Stats Insider provides full betting coverage of the Milwaukee vs St. Louis game on Monday, including data-driven predictions and expert tips.
Our model updates frequently, so keep checking this article for the latest betting analysis before the Milwaukee vs St. Louis match-up.
As always, see our Best Bets to get the best tips on every MLB game, as well as predictions for a wide range of other sports.
Brewers vs Cardinals: Essential Details
The game between the Brewers and Cardinals at American Family Field is scheduled to start at 4:10am AEST on Monday.
- Teams: Milwaukee Brewers vs St. Louis Cardinals
- Date: Monday 15 September 2025
- Time: 4:10am AEST
- Venue: American Family Field
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Milwaukee vs St. Louis predictions are based on 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.
If you decide to use our predictions for betting purposes, it's vital that you gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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