Blue Jays vs Padres Prediction and MLB Tips - 22 May 2025
Last updated: May 21, 2025, 11:09PM | Published: May 21, 2025, 12:30AM
The Toronto Blue Jays will face the San Diego Padres in MLB action at Rogers Centre on Thursday, beginning at 9:07am AEST.
The Blue Jays will have Kevin Gausman (3-4, 4.59 ERA) start, up against Randy Vásquez (3-3, 3.45 ERA) for the Padres.
This article features Stats Insider's prediction and tips for the Blue Jays vs Padres game, plus the latest betting odds in Australia.
Who Will Win?
Using advanced machine learning and data, Stats Insider has simulated the result of Thursday's Toronto vs San Diego MLB game 10,000 times.
Our proven predictive analytics model currently gives the Blue Jays a 58% chance of winning against the Padres at Rogers Centre.
Blue Jays vs Padres: Odds
The latest betting odds in Australia for Thursday's MLB game at Rogers Centre are listed here:
- Head to Head: Blue Jays $1.61, Padres $2.40
- Line: Blue Jays -1.5 ($2.25), Padres +1.5 ($1.67)
- Total (Over/Under 9 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Blue Jays at $1.61 and the Padres at $2.40.
The Blue Jays are 1.5-run favourites against the Padres, with odds of $2.25 available at TAB.
For the underdog Padres (+1.5) to cover the line, TAB offers odds of $1.67.
The over/under for total runs scored is set at 9 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Padres (+1.5) are predicted to cover the line 60% of the time, while the 9-run over/under is expected to stay under 54% of the time.
Blue Jays vs Padres: Best Bets
- Head to Head: San Diego at $2.40 with TAB
- Line: Padres +1.5 at $1.67 with TAB
- Total Runs: Under 9 at $1.91 with TAB
Today's Blue Jays vs Padres best bets are based on complex simulations and wagering intelligence to bring you the best possible advice around the clock.
While the Blue Jays have a higher chance of winning the game, betting on the Padres to win is our recommended option because of the 2.2% edge identified when comparing our data-led probabilities to the odds currently available.
Taking advantage of the edges seen on Stats Insider is pivotal to achieving long-term profitability.
Blue Jays vs Padres: Prediction
Stats Insider provides full coverage of the Toronto vs San Diego game on Thursday, including data-driven predictions and live win probabilitiestips.
Our model updates frequently, so bookmark this page for the latest betting tips before the Toronto vs San Diego game.
As always, see Stats Insider's Best Bets for the best tips for every MLB game, as well as predictions for a wide range of other sports.
Blue Jays vs Padres: Essential Details
The game between the Blue Jays and Padres at Rogers Centre is scheduled to begin at 9:07am AEST on Thursday.
- Teams: Toronto Blue Jays vs San Diego Padres
- Date: Thursday 22 May 2025
- Time: 9:07am AEST
- Venue: Rogers Centre
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our Toronto vs San Diego predictions have been made based on 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are trustworthy and reliable, giving you the knowledge you need to make informed decisions with confidence.
If you choose to use our MLB predictions for betting purposes, it's important to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
More on MLB
Stats Insider is your home for betting on the MLB in Australia, with the latest MLB betting news, tips for every MLB game, and futures odds for the MLB.