Blue Jays vs Padres Prediction and MLB Tips - 21 May 2025
Last updated: May 20, 2025, 11:09PM | Published: May 20, 2025, 8:29AM
The Toronto Blue Jays will take on the San Diego Padres in MLB action at Rogers Centre on Wednesday, commencing at 9:07am AEST.
The Blue Jays will send Chris Bassitt (3-2, 3.16 ERA) to the mound, while the Padres are going with Dylan Cease (1-2, 4.60 ERA).
This article features Stats Insider's top betting tips for the Blue Jays vs Padres game, plus the latest betting odds in Australia.
Who Will Win?
Based on trusted machine learning and data, Stats Insider has simulated the outcome of Wednesday's Toronto vs San Diego MLB game 10,000 times.
Our independent predictive analytics model gives the Padres a 52% chance of winning against the Blue Jays at Rogers Centre.
Blue Jays vs Padres: Odds
The current betting odds in Australia for Wednesday's MLB game at Rogers Centre are shown below:
- Head to Head: Blue Jays $1.95, Padres $1.87
- Line: Blue Jays +1.5 ($1.56), Padres -1.5 ($2.50)
- Total (Over/Under 7.5 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Blue Jays at $1.95 and the Padres at $1.87.
The Blue Jays are listed as 1.5-run underdogs against the Padres, with odds of $1.56 available at TAB.
For the favourite Padres (-1.5) to cover the line, TAB offers odds of $2.50.
The over/under for total runs scored is set at 7.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Blue Jays (+1.5) are predicted to cover the line 62% of the time, while the 7.5-run over/under is expected to go over 51% of the time.
Blue Jays vs Padres: Best Bets
- Head to Head: San Diego at $1.87 with TAB
- Line: Blue Jays +1.5 at $1.56 with TAB
- Total Runs: Under 7.5 at $1.91 with TAB
These Blue Jays vs Padres best bets are based on market-leading modelling and betting expertise to provide you with the best possible advice around the clock.
Despite the Over being more likely to hit in this game, Under 7.5 is our best bet due to the better odds ($1.91) that are available from TAB.
Blue Jays vs Padres: Prediction
Stats Insider provides full betting coverage of the Toronto vs San Diego game on Wednesday, including data-driven predictions and expert tips.
Remember, our model updates regularly, so refresh this page for the latest betting tips before the Toronto vs San Diego match-up.
As always, see Stats Insider's Best Bets to get the best tips for every MLB game, as well as predictions for a wide range of other sports.
Blue Jays vs Padres: Essential Details
The match-up between the Blue Jays and Padres at Rogers Centre is scheduled to begin at 9:07am AEST on Wednesday.
- Teams: Toronto Blue Jays vs San Diego Padres
- Date: Wednesday 21 May 2025
- Time: 9:07am AEST
- Venue: Rogers Centre
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our Toronto vs San Diego predictions have been made thanks to 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.
If you choose to use our MLB predictions for betting purposes, it's important to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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