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Blue Jays vs Astros Prediction and MLB Tips - 10 September 2025

The Toronto Blue Jays will take on the Houston Astros in MLB action at Rogers Centre on Wednesday, commencing at 9:07am AEST.

Shane Bieber (2-1, 4.15 ERA) will get the ball for the Blue Jays, while the Astros will counter with Luis Garcia (1-0, 4.50 ERA).

This article features Stats Insider's prediction and tips for the Blue Jays vs Astros game, plus the latest betting odds in Australia.

Who Will Win?

Using trusted computer power and data, Stats Insider has simulated the result of Wednesday's Toronto vs Houston MLB match-up 10,000 times.

Our leading predictive analytics model gives the Blue Jays a 56% chance of beating the Astros at Rogers Centre.

Blue Jays vs Astros: Odds

The latest betting odds in Australia for Wednesday's MLB game at Rogers Centre are listed here:

  • Head to Head: Blue Jays $1.67, Astros $2.25
  • Line: Blue Jays -1.5 ($2.40), Astros +1.5 ($1.61)
  • Total (Over/Under 8 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Blue Jays at $1.67 and the Astros at $2.25.

The Blue Jays are 1.5-run favourites against the Astros, with odds of $2.40 available at TAB.

For the underdog Astros (+1.5) to cover the line, TAB offers odds of $1.61.

The over/under for total runs scored is set at 8 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Astros (+1.5) are predicted to cover the line 62% of the time, while the 8-run over/under is expected to go over 53% of the time.

Blue Jays vs Astros: Betting Tips

  • Head to Head: Houston at $2.25 with TAB
  • Line: Astros +1.5 at $1.61 with TAB
  • Total Runs: Over 8 at $1.91 with TAB

Today's Blue Jays vs Astros betting tips are based on complex simulations and betting expertise to help you place better bets with your chosen online bookie.

While the Blue Jays have a higher chance of winning the game, betting on the Astros to win is our recommended option due to the 1.7% edge identified when comparing our data-led probabilities to the odds currently on offer.

Making use of the edges published on Stats Insider is one of the keys to being profitable in the long run.

Blue Jays vs Astros: Prediction

Stats Insider provides full coverage of the Toronto vs Houston game on Wednesday, including data-driven predictions and the best betting tips.

Remember, our model updates regularly, so refresh this page for the latest betting predictions before the Toronto vs Houston match-up.

As always, see Stats Insider's Best Bets to get betting tips for every MLB game, plus predictions for a wide range of other sports.

Blue Jays vs Astros: Essential Details

The game between the Blue Jays and Astros at Rogers Centre is scheduled to start at 9:07am AEST on Wednesday.

All dates and times in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our Toronto vs Houston predictions have been made thanks to 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the knowledge you need to make informed decisions with confidence.

If you choose to use our MLB predictions for betting purposes, it's vital to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, tips for every MLB game, and futures probabilities for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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