Bills vs Dolphins Prediction and Preview - NFL Week 3, 2025
Last updated: Sep 15, 2025, 8:36AM | Published: Sep 12, 2025, 4:03AM
The Buffalo Bills will take on the Miami Dolphins in NFL Week 3 action at Highmark Stadium on Friday, beginning at 10:15am AEST.
This article features Stats Insider's prediction and tips for the Bills vs Dolphins game, as well as the latest betting odds in Australia.
Who Will Win?
Using advanced computer power and data, Stats Insider has simulated the outcome of Friday's Buffalo vs Miami NFL game 10,000 times.
Our leading predictive analytics model currently gives the Bills a 74% chance of winning against the Dolphins at Highmark Stadium.
Bills vs Dolphins: Odds
The current Bet365 betting odds in Australia for Friday's NFL game at Highmark Stadium are listed below:
- Head to Head: Bills $1.12, Dolphins $6.75
- Line: Bills -12.5 ($1.91), Dolphins +12.5 ($1.91)
- Total (Over/Under 49.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Bills at $1.12 and the Dolphins at $6.75.
The Bills are 12.5-point favourites against the Dolphins, with odds of $1.91 available at Bet365.
For the underdog Dolphins (+12.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 49.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Dolphins (+12.5) are predicted to cover the line 63% of the time, while the 49.5-point over/under is expected to stay under 52% of the time.
Bills vs Dolphins: Best Bets
- Head to Head: Miami at $6.75 with Bet365
- Line: Dolphins +12.5 at $1.91 with Bet365
- Total Points: Under 49.5 at $1.91 with Bet365
If you see a 🔥, you know you've found one of our best tips for today across any sport.
Stats Insider's Bills vs Dolphins betting tips are based on complex modelling and gambling experience to help you place more informed bets with your chosen online bookie.
While the Bills have a higher chance of winning the game, betting on the Dolphins to win is our preferred option because of the 10.7% edge identified when comparing our data-led probabilities to the odds currently on offer.
Making use of the edges seen on Stats Insider is one of the keys to being profitable in the long run.
Bills vs Dolphins: Prediction
Stats Insider's predicted final score for Bills vs Dolphins at Highmark Stadium in Week 3 is the Bills winning 27-20.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full coverage of the Buffalo vs Miami game in Week 3, including data-driven predictions and the best betting tips.
18+. Odds correct at time of publishing and subject to change.Our model updates frequently, so refresh this article for the latest betting predictions before the Buffalo vs Miami match-up.
As always, see Stats Insider's Best Bets to get the best tips for every NFL game, plus predictions for a wide range of other sports.
Bills vs Dolphins: Week 3 Essential Details
The NFL Week 3 game between the Bills and Dolphins at Highmark Stadium is scheduled to commence at 10:15am AEST on Friday.
- Teams: Buffalo Bills vs Miami Dolphins
- Date: Friday 19 September 2025
- Time: 10:15am AEST
- Venue: Highmark Stadium
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our Buffalo vs Miami predictions are the result of 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our NFL tips are trustworthy and reliable, giving you the knowledge you need to make informed decisions with confidence.
If you decide to use our NFL predictions for betting purposes, it's important that you gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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