Bills vs Chiefs Prediction and Preview - NFL Week 9, 2025
Last updated: Nov 2, 2025, 9:25PM | Published: Oct 26, 2025, 4:06AM
The Buffalo Bills will take on the Kansas City Chiefs in NFL Week 9 action at Highmark Stadium on Monday, commencing at 8:25am AEDT.
This article features Stats Insider's prediction and tips for the Bills vs Chiefs game, as well as the latest betting odds and touchdown scorer tips.
Who Will Win?
Utilising advanced machine learning and data, Stats Insider has simulated the outcome of Monday's Buffalo vs Kansas City NFL match-up 10,000 times.
Our independent predictive analytics model currently gives the Chiefs a 56% chance of winning against the Bills in Week 9 of the NFL season.
Bills vs Chiefs: Odds
The current Bet365 betting odds in Australia for Monday's NFL game at Highmark Stadium are shown here:
- Head to Head: Bills $2.15, Chiefs $1.74
- Line: Bills +2.5 ($1.91), Chiefs -2.5 ($1.91)
- Total (Over/Under 53 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Bills at $2.15 and the Chiefs at $1.74.
The Bills are 2.5-point underdogs against the Chiefs, with odds of $1.91 available at Bet365.
For the favourite Chiefs (-2.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 53 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's analytics model, the Bills (+2.5) are predicted to cover the line 58% of the time, while the 53-point over/under is expected to stay under 51% of the time.
Bills vs Chiefs: Betting Tips
- Head to Head: Kansas City at $1.74 with Bet365
- Line: Bills +2.5 at $1.91 with Bet365
- Total Points: Under 53 at $1.91 with Bet365
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Our Bills vs Chiefs betting tips are based on world-class modelling and wagering expertise to give you the best possible advice 24/7.
Bills vs Chiefs: Prediction
Stats Insider's predicted final score for Bills vs Chiefs at Highmark Stadium in Week 9 is the Chiefs winning 27-25.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full betting coverage of the Buffalo vs Kansas City game in Week 9, including data-driven predictions and top betting tips.
Get expert analysis from the US with Dimers' in-depth Bills vs Chiefs prediction.
18+. Odds correct at time of publishing and subject to change.Bills vs Chiefs: TD Scorer Tips
Who will score the first touchdown in Bills vs Chiefs? The data is in.
According to Stats Insider, Buffalo's James Cook is the most likely player to score the first touchdown in Bills vs Chiefs.
Cook has a 10.9% chance of scoring the first TD at Highmark Stadium, while the Bills RB has a 54.4% chance of scoring an anytime touchdown.
Scroll down for our complete list of first touchdown scorer and anytime touchdown scorer probabilities.
First Touchdown Scorer Tips
Bills First TD Tips
- James Cook: 10.9% probability
- Josh Allen: 6.8% probability
- Khalil Shakir: 5.1% probability
- Dalton Kincaid: 4.4% probability
- Keon Coleman: 4.1% probability
Chiefs First TD Tips
- Rashee Rice: 10.0% probability
- Kareem Hunt: 9.2% probability
- Travis Kelce: 7.0% probability
- Xavier Worthy: 5.9% probability
- Brashard Smith: 3.9% probability
Anytime Touchdown Scorer Tips
Bills Anytime TD Tips
- James Cook: 54.4% probability
- Josh Allen: 38.5% probability
- Khalil Shakir: 30.8% probability
- Dalton Kincaid: 27.1% probability
- Keon Coleman: 25.3% probability
Chiefs Anytime TD Tips
- Rashee Rice: 47.9% probability
- Kareem Hunt: 45.2% probability
- Travis Kelce: 36.9% probability
- Xavier Worthy: 32.0% probability
- Brashard Smith: 22.5% probability
Bills-Chiefs Projected Player Stats
Of the starting quarterbacks, the Bills' Josh Allen is projected for 242 passing yards. The Chiefs' Patrick Mahomes is expected to throw for 277 yards.
Bills Starting QB
- Josh Allen: 242 projected passing yards
Chiefs Starting QB
- Patrick Mahomes: 277 projected passing yards
Bills Rushing Yards
- James Cook: 76 projected yards
- Josh Allen: 43 projected yards
- Ty Johnson: 15 projected yards
Chiefs Rushing Yards
- Kareem Hunt: 47 projected yards
- Patrick Mahomes: 31 projected yards
- Brashard Smith: 21 projected yards
Bills Receiving Yards
- Khalil Shakir: 56 projected yards
- Keon Coleman: 47 projected yards
- Dalton Kincaid: 41 projected yards
- Elijah Moore: 23 projected yards
- Tyrell Shavers: 19 projected yards
Chiefs Receiving Yards
- Rashee Rice: 77 projected yards
- Xavier Worthy: 52 projected yards
- Travis Kelce: 47 projected yards
- Hollywood Brown: 26 projected yards
- Brashard Smith: 20 projected yards
Remember, our model updates frequently, so keep checking this article for the latest betting tips before the Buffalo vs Kansas City match-up.
As always, see our Best Bets for betting tips on every NFL game, plus predictions for a wide range of other sports.
Bills vs Chiefs: Week 9 Essential Details
The NFL Week 9 match-up between the Bills and Chiefs at Highmark Stadium is scheduled to start at 8:25am AEDT on Monday.
- Teams: Buffalo Bills vs Kansas City Chiefs
- Date: Monday 3 November 2025
- Time: 8:25am AEDT
- Venue: Highmark Stadium
All dates and times mentioned in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.
Conclusion
Our Buffalo vs Kansas City predictions have been made based on 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our NFL tips are accurate and reliable, giving you the knowledge you need to make informed decisions with confidence.
If you choose to use our NFL predictions for betting purposes, it's crucial to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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