Bills vs Buccaneers Prediction and Preview - NFL Week 11, 2025
Last updated: Nov 9, 2025, 10:03AM | Published: Nov 9, 2025, 5:01AM
The Buffalo Bills will sqaure off with the Tampa Bay Buccaneers in NFL Week 11 action at Highmark Stadium on Monday, November 17, commencing at 5:00am AEDT.
This article features Stats Insider's free betting tips for the Bills vs Buccaneers game, plus the latest betting odds in Australia.
Who Will Win?
Based on trusted computer power and data, Stats Insider has simulated the outcome of Buccaneers vs Bills 10,000 times.
Our leading predictive analytics model currently gives the Bills a 66% chance of defeating the Buccaneers at Highmark Stadium.
Bills vs Buccaneers: Odds
The latest Bet365 betting odds in Australia for this NFL game at Highmark Stadium are shown here:
- Head to Head: Bills $1.37, Buccaneers $3.20
- Line: Bills -6 ($1.91), Buccaneers +6 ($1.91)
- Total (Over/Under 50.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Bills at $1.37 and the Buccaneers at $3.20.
The Bills are listed as 6-point favourites against the Buccaneers, with odds of $1.91 available at Bet365.
For the underdog Buccaneers (+6) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 50.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Buccaneers (+6) are predicted to cover the line 57% of the time, while the 50.5-point over/under is expected to stay under 52% of the time.
Bills vs Buccaneers: Betting Tips
- Head to Head: Tampa Bay at $3.20 with Bet365
- Line: Buccaneers +6 at $1.91 with Bet365
- Total Points: Under 50.5 at $1.91 with Bet365
When you see a 🔥, you know you've found one of our best bets for today across any sport.
Our Bills vs Buccaneers predictions are based on market-leading modelling and gambling intelligence to help you place better bets with your chosen online bookie.
While the Bills have a higher chance of winning the game, betting on the Buccaneers to win is our recommended option because of the 3.2% edge found when comparing our data-led probabilities to the odds currently on offer.
Making use of the edges seen here at Stats Insider is one of the keys to achieving long-term success as a punter.
Bills vs Buccaneers: Prediction
Stats Insider's predicted final score for Bills vs Buccaneers at Highmark Stadium in Week 11 is the Bills winning 27-22.
This prediction is based on each team's average score from 10,000 game simulations.
Stats Insider provides full coverage of the Buffalo vs Tampa Bay game in Week 11, including data-driven predictions and top betting tips.
18+. Odds correct at time of publishing and subject to change.Remember, our model updates frequently, so keep checking this article for the latest betting analysis before the Buffalo vs Tampa Bay game.
As always, see our Best Bets to get the best tips for every NFL game, as well as predictions for a wide range of other sports.
Bills vs Buccaneers: Week 11 Essential Details
The NFL Week 11 match-up between the Bills and Buccaneers at Highmark Stadium is scheduled to begin at 5:00am AEDT on Monday, November 17.
- Teams: Buffalo Bills vs Tampa Bay Buccaneers
- Date: Monday 17 November 2025
- Time: 5:00am AEDT
- Venue: Highmark Stadium
All dates and times mentioned in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise stated.
Conclusion
Our Buffalo vs Tampa Bay predictions have been made after running 10,000 data-driven simulations of the game, all curated by our team of expert data scientists and analysts. We use cutting-edge technology and machine learning to ensure our NFL tips are trustworthy and reliable, so that you can make informed decisions with confidence.
If you choose to use our predictions for betting purposes, it's important to gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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