Bills vs 49ers Prediction and Preview - NFL Week 13, 2024
Last updated: Dec 2, 2024, 1:20AM | Published: Nov 25, 2024, 5:00AM
The Buffalo Bills will take on the San Francisco 49ers in NFL Week 13 action at Highmark Stadium on Monday, commencing at 12:20pm AEDT.
This article features Stats Insider's prediction and tips for the Bills vs 49ers game, plus the latest betting odds and touchdown scorer tips.
Who Will Win?
Using advanced computer power and data, Stats Insider has simulated the result of Monday's Buffalo vs San Francisco NFL match-up 10,000 times.
Our proven predictive analytics model gives the Bills a 74% chance of defeating the 49ers at Highmark Stadium.
Bills vs 49ers: Odds
The current Bet365 betting odds in Australia for Monday's NFL game at Highmark Stadium are shown here:
- Head to Head: Bills $1.31, 49ers $3.60
- Line: Bills -6.5 ($1.91), 49ers +6.5 ($1.91)
- Total (Over/Under 45.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the Bills at $1.31 and the 49ers at $3.60.
The Bills are 6.5-point favourites against the 49ers, with odds of $1.91 available at Bet365.
For the underdog 49ers (+6.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 45.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the bookies have got it right and both the Bills and the 49ers have a 50% chance of covering the line.
The 45.5-point over/under is expected to stay under 51% of the time.
Bills vs 49ers: Best Bets
- Head to Head: San Francisco at $3.60 with Bet365
- Line: 49ers +6.5 at $1.91 with Bet365
- Total Points: Under 45.5 at $1.91 with Bet365
While the Bills have a higher chance of winning the game, betting on the 49ers to win is our recommended option due to the edge identified when comparing our data-driven probabilities to the odds currently available.
Taking advantage of the edges seen on Stats Insider is crucial to being profitable in the long run.
Bills vs 49ers: Prediction
Stats Insider's predicted final score for Bills vs 49ers at Highmark Stadium in Week 13 is the Bills prevailing 26-19.
This prediction is based on each team's average score from 10,000 game simulations.
Stats Insider provides full betting coverage of the Buffalo vs San Francisco game in Week 13, including data-driven predictions and computer tips.
Bills vs 49ers: TD Scorer Tips
Who will score an anytime touchdown in Bills vs 49ers? The data is in.
According to Stats Insider, San Francisco's Christian McCaffrey is the most likely player to score the first TD in Bills vs 49ers.
McCaffrey has a 12.5% chance of scoring the first TD at Highmark Stadium, while the 49ers RB has a 50.4% chance of reaching the end zone at any point during the game.
Scroll down for our complete list of first touchdown scorer and anytime touchdown scorer probabilities.
First Touchdown Scorer Tips
Bills First TD Tips
- Josh Allen: 11.0% probability
- James Cook: 10.6% probability
- Amari Cooper: 7.2% probability
- Khalil Shakir: 6.5% probability
- Dawson Knox: 5.5% probability
49ers First TD Tips
- Christian McCaffrey: 12.5% probability
- Deebo Samuel: 7.1% probability
- George Kittle: 6.5% probability
- Jauan Jennings: 6.2% probability
- Brock Purdy: 3.9% probability
Anytime Touchdown Scorer Tips
Bills Anytime TD Tips
- Josh Allen: 45.6% probability
- James Cook: 43.8% probability
- Amari Cooper: 31.0% probability
- Khalil Shakir: 29.9% probability
- Dawson Knox: 25.6% probability
49ers Anytime TD Tips
- Christian McCaffrey: 50.4% probability
- Deebo Samuel: 32.0% probability
- George Kittle: 29.2% probability
- Jauan Jennings: 28.3% probability
- Brock Purdy: 19.0% probability
Bills-49ers Projected Player Stats
Of the starting quarterbacks, the Bills' Josh Allen is projected for 243 passing yards, while the 49ers' Brock Purdy is expected to throw for 250 yards.
Bills Starting QB
- Josh Allen: 243 projected passing yards
49ers Starting QB
- Brock Purdy: 250 projected passing yards
Bills Rushing Yards
- James Cook: 69 projected yards
- Josh Allen: 36 projected yards
- Ray Davis: 23 projected yards
49ers Rushing Yards
- Christian McCaffrey: 81 projected yards
- Brock Purdy: 20 projected yards
- Deebo Samuel: 10 projected yards
Bills Receiving Yards
- Khalil Shakir: 61 projected yards
- Amari Cooper: 53 projected yards
- Dawson Knox: 36 projected yards
- Mack Hollins: 23 projected yards
- Curtis Samuel: 22 projected yards
49ers Receiving Yards
- George Kittle: 54 projected yards
- Jauan Jennings: 51 projected yards
- Deebo Samuel: 44 projected yards
- Christian McCaffrey: 29 projected yards
- Ricky Pearsall: 23 projected yards
Remember, our model updates frequently, so keep checking this page for the latest betting tips before the Buffalo vs San Francisco game.
As always, see Stats Insider's Best Bets for the best tips on every NFL game, as well as predictions for a wide range of other sports.
Bills vs 49ers: Week 13 Essential Details
The NFL Week 13 game between the Bills and 49ers at Highmark Stadium is scheduled to start at 12:20pm AEDT on Monday.
- Teams: Buffalo Bills vs San Francisco 49ers
- Date: Monday 2 December 2024
- Time: 12:20pm AEDT
- Venue: Highmark Stadium
All dates and times in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.
Conclusion
Our Buffalo vs San Francisco predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our NFL tips are trustworthy and reliable, so that you can make informed decisions with confidence.
If you choose to use our NFL predictions for betting purposes, it's important to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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