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Astros vs Guardians Prediction and MLB Tips - 9 July 2025

The Houston Astros will sqaure off with the Cleveland Guardians in MLB action at Daikin Park on Wednesday, beginning at 10:10am AEST.

The Astros will send Hunter Brown (9-3, 1.82 ERA) to the mound, while the Guardians are going with Joey Cantillo (1-0, 3.41 ERA).

This article features Stats Insider's best betting tips for the Astros vs Guardians game, as well as the latest betting odds in Australia.

Who Will Win?

Utilising trusted computer power and data, Stats Insider has simulated the result of Wednesday's Houston vs Cleveland MLB match-up 10,000 times.

Our independent predictive analytics model currently gives the Astros a 64% chance of defeating the Guardians at Daikin Park.

Astros vs Guardians: Odds

The latest betting odds in Australia for Wednesday's MLB game at Daikin Park are shown below:

  • Head to Head: Astros $1.48, Guardians $2.70
  • Line: Astros -1.5 ($2.02), Guardians +1.5 ($1.78)
  • Total (Over/Under 7 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Astros at $1.48 and the Guardians at $2.70.

The Astros are 1.5-run favourites against the Guardians, with odds of $2.02 available at TAB.

For the underdog Guardians (+1.5) to cover the line, TAB offers odds of $1.78.

The over/under for total runs scored is set at 7 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Guardians (+1.5) are predicted to cover the line 55% of the time, while the 7-run over/under is expected to stay under 51% of the time.

Astros vs Guardians: Best Bets

  • Head to Head: Cleveland at $2.70 with TAB
  • Line: Guardians +1.5 at $1.78 with TAB
  • Total Runs: Under 7 at $1.91 with TAB

These Astros vs Guardians betting tips are based on detailed modelling and gambling intelligence to give you the best possible advice around the clock.

While the Astros have a higher chance of winning the game, betting on the Guardians to win is our recommended option due to the edge identified when comparing our data-driven probabilities to the odds currently on offer.

Making use of the edges seen on Stats Insider is one of the keys to being profitable in the long run.

Astros vs Guardians: Prediction

Stats Insider provides full betting coverage of the Houston vs Cleveland game on Wednesday, including data-driven predictions and expert tips.

Remember, our model updates regularly, so bookmark this article for the latest betting analysis before the Houston vs Cleveland game.

As always, see our Best Bets to get the best tips on every MLB game, as well as predictions for a wide range of other sports.

Astros vs Guardians: Essential Details

The match-up between the Astros and Guardians at Daikin Park is scheduled to commence at 10:10am AEST on Wednesday.

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.

Conclusion

Our Houston vs Cleveland predictions have been made thanks to 10,000 data-driven simulations of the game, carefully curated by our team of expert data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.

If you decide to use our predictions for betting purposes, it's vital to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, predictions for every MLB game, and futures odds for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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