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Astros vs Guardians Prediction and MLB Tips - 10 July 2025

The Houston Astros will face the Cleveland Guardians in MLB action at Daikin Park on Thursday, beginning at 10:10am AEST.

Brandon Walter (1-1, 4.15 ERA) will be on the bump for the Astros, while the Guardians will counter with Slade Cecconi (3-4, 3.56 ERA).

This article features Stats Insider's prediction and tips for the Astros vs Guardians game, as well as the latest betting odds in Australia.

Who Will Win?

Using advanced computer power and data, Stats Insider has simulated the outcome of Thursday's Houston vs Cleveland MLB match-up 10,000 times.

Our leading predictive analytics model gives the Astros a 59% chance of winning against the Guardians at Daikin Park.

Astros vs Guardians: Odds

The current betting odds in Australia for Thursday's MLB game at Daikin Park are listed below:

  • Head to Head: Astros $1.62, Guardians $2.35
  • Line: Astros -1.5 ($2.45), Guardians +1.5 ($1.59)
  • Total (Over/Under 7.5 Runs): Over $1.91, Under $1.91

Odds are correct at the time of publication and subject to change.

Looking at the latest head-to-head odds, the bookmakers currently have the Astros at $1.62 and the Guardians at $2.35.

The Astros are 1.5-run favourites against the Guardians, with odds of $2.45 available at TAB.

For the underdog Guardians (+1.5) to cover the line, TAB offers odds of $1.59.

The over/under for total runs scored is set at 7.5 with TAB, which has odds of $1.91 for the over and $1.91 for the under.

According to Stats Insider's analytics model, the Guardians (+1.5) are predicted to cover the line 61% of the time, while the 7.5-run over/under is expected to stay under 53% of the time.

Astros vs Guardians: Betting Tips

  • Head to Head: Cleveland at $2.35 with TAB
  • Line: Guardians +1.5 at $1.59 with TAB
  • Total Runs: Under 7.5 at $1.91 with TAB

Today's Astros vs Guardians betting tips are based on detailed modelling and betting experience to help you place better bets with your chosen online bookie.

While the Astros have a higher chance of winning the game, betting on the Guardians to win is our recommended option due to the edge found when comparing our data-driven probabilities to the odds currently on offer.

Making use of the edges seen here at Stats Insider is crucial to being profitable in the long run.

Astros vs Guardians: Prediction

Stats Insider provides full betting coverage of the Houston vs Cleveland game on Thursday, including data-driven predictions and expert tips.

Remember, our model updates regularly, so bookmark this page for the latest betting tips before the Houston vs Cleveland match-up.

As always, see Stats Insider's Best Bets to get betting tips on every MLB game, plus predictions for a wide range of other sports.

Astros vs Guardians: Essential Details

The game between the Astros and Guardians at Daikin Park is scheduled to commence at 10:10am AEST on Thursday.

All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.

Conclusion

Our Houston vs Cleveland predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of skilled data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the knowledge you need to make informed decisions with confidence.

If you choose to use our predictions for betting purposes, it's important to gamble responsibly and keep track of your money. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.

More on MLB

Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, tips for every MLB game, and futures probabilities for the MLB.

Stats Insider

Stats Insider, Australia's leading predictive analytics website, offers Australian sports fans innovative tools and content to enhance their enjoyment of major sporting events both domestically and internationally. Our goal is to transform the sports fan experience by providing readily accessible, data-driven content for sports enthusiasts like us.

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