Angels vs Astros Prediction and MLB Tips - 29 September 2025
Last updated: Sep 28, 2025, 7:09PM | Published: Sep 28, 2025, 8:28AM
The Los Angeles Angels will sqaure off with the Houston Astros in Game of the League Series at Angel Stadium on Monday, beginning at 5:07am AEST.
Sam Aldegheri (0-1, 8.00 ERA) will be on the bump for the Angels, pitting him against Lance McCullers (2-5, 6.71 ERA) for the Astros.
This article features Stats Insider's prediction and tips for the Angels vs Astros game, along with the latest betting odds in Australia.
Who Will Win?
Using advanced machine learning and data, Stats Insider has simulated the outcome of Monday's LA Angels vs Houston MLB game 10,000 times.
Our leading predictive analytics model gives the Astros a 53% chance of beating the Angels at Angel Stadium.
Angels vs Astros: Odds
The latest betting odds in Australia for Monday's MLB game at Angel Stadium are listed below:
- Head to Head: Angels $1.95, Astros $1.87
- Line: Angels +1.5 ($1.62), Astros -1.5 ($2.35)
- Total (Over/Under 9 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Angels at $1.95 and the Astros at $1.87.
The Angels are 1.5-run underdogs against the Astros, with odds of $1.62 available at TAB.
For the favourite Astros (-1.5) to cover the line, TAB offers odds of $2.35.
The over/under for total runs scored is set at 9 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Angels (+1.5) are predicted to cover the line 57% of the time, while the 9-run over/under is expected to go over 57% of the time.
Angels vs Astros: Betting Tips
- Head to Head: Houston at $1.87 with TAB
- Line: Astros -1.5 at $2.35 with TAB
- Total Runs: Over 9 at $1.91 with TAB
Today's Angels vs Astros predictions are based on world-class simulations and gambling intelligence to help you place smarter bets with your chosen online bookie.
Even though the Angels are more likely to cover the line, our best bet of Astros -1.5 is based on the likelihood of that happening, as suggested by our predictive analytics model, and the top odds available.
Angels vs Astros: Prediction
Stats Insider provides full betting coverage of the LA Angels vs Houston game on Monday, including data-driven predictions and expert tips.
Remember, our model updates regularly, so keep checking this article for the latest betting analysis before the LA Angels vs Houston match-up.
As always, see our Best Bets to get betting tips on every MLB game, as well as predictions for a wide range of other sports.
Angels vs Astros: Essential Details
The game between the Angels and Astros at Angel Stadium is scheduled to begin at 5:07am AEST on Monday.
- Teams: Los Angeles Angels vs Houston Astros
- Date: Monday 29 September 2025
- Time: 5:07am AEST
- Venue: Angel Stadium
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise noted.
Conclusion
Our LA Angels vs Houston predictions have been made after running 10,000 data-driven simulations of the game, all curated by our team of skilled data scientists and analysts. We use cutting-edge technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the knowledge you need to make informed decisions with confidence.
If you choose to use our MLB predictions for betting purposes, it's vital that you gamble responsibly and manage your finances effectively. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
More on MLB
Stats Insider is your go-to source for betting on the MLB in Australia, with the latest MLB betting news, tips for every MLB game, and futures probabilities for the MLB.
