Angels vs Astros Prediction and MLB Tips - 27 September 2025
Last updated: Sep 27, 2025, 1:35AM | Published: Sep 26, 2025, 3:29AM
The Los Angeles Angels will take on the Houston Astros in Game of the League Series at Angel Stadium on Saturday, beginning at 11:38am AEST.
Kyle Hendricks (8-10, 4.79 ERA) will start for the Angels, up against Jason Alexander (4-2, 4.83 ERA) for the Astros.
This article features Stats Insider's top betting tips for the Angels vs Astros game, as well as the latest betting odds in Australia.
Who Will Win?
Using advanced computer power and data, Stats Insider has simulated the outcome of Saturday's LA Angels vs Houston MLB match-up 10,000 times.
Our proven predictive analytics model gives the Astros a 56% chance of beating the Angels at Angel Stadium.
Angels vs Astros: Odds
The latest betting odds in Australia for Saturday's MLB game at Angel Stadium are listed here:
- Head to Head: Angels $2.10, Astros $1.77
- Line: Angels +1.5 ($1.72), Astros -1.5 ($2.20)
- Total (Over/Under 9 Runs): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, the bookmakers currently have the Angels at $2.10 and the Astros at $1.77.
The Angels are 1.5-run underdogs against the Astros, with odds of $1.72 available at TAB.
For the favourite Astros (-1.5) to cover the line, TAB offers odds of $2.20.
The over/under for total runs scored is set at 9 with TAB, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the Angels (+1.5) are predicted to cover the line 55% of the time, while the 9-run over/under is expected to go over 55% of the time.
Angels vs Astros: Betting Tips
- Head to Head: Houston at $1.77 with TAB
- Line: Astros -1.5 at $2.20 with TAB
- Total Runs: Over 9 at $1.91 with TAB
Stats Insider's Angels vs Astros predictions are based on complex simulations and wagering expertise to help you place smarter bets with your chosen online bookie.
Although the Angels are more likely to cover the line, our best bet of Astros -1.5 is based on the chance of that happening, as suggested by our predictive analytics model, and the top odds available.
Angels vs Astros: Prediction
Stats Insider provides full coverage of the LA Angels vs Houston game on Saturday, including data-driven predictions and live updatestips.
Remember, our model updates frequently, so keep checking this page for the latest betting predictions before the LA Angels vs Houston game.
As always, see Stats Insider's Best Bets for betting tips for every MLB game, as well as predictions for a wide range of other sports.
Angels vs Astros: Essential Details
The game between the Angels and Astros at Angel Stadium is scheduled to begin at 11:38am AEST on Saturday.
- Teams: Los Angeles Angels vs Houston Astros
- Date: Saturday 27 September 2025
- Time: 11:38am AEST
- Venue: Angel Stadium
All dates and times mentioned in this article are in Australian Eastern Standard Time (AEST), unless otherwise stated.
Conclusion
Our LA Angels vs Houston predictions have been made after running 10,000 data-driven simulations of the game, all curated by our team of experienced data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our MLB tips are accurate and reliable, giving you the confidence to make informed decisions.
If you decide to use our MLB predictions for betting purposes, it's vital that you gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
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