49ers vs Bears Prediction and Preview - NFL Week 17, 2025
Last updated: Dec 29, 2025, 1:21AM | Published: Dec 22, 2025, 5:00AM
The San Francisco 49ers will sqaure off with the Chicago Bears in NFL Week 17 action at Levi's Stadium on Monday, beginning at 12:20pm AEDT.
This article features Stats Insider's free betting tips for the 49ers vs Bears game, along with the latest betting odds and touchdown scorer tips.
Who Will Win?
Utilising trusted computer power and data, Stats Insider has simulated the outcome of Monday's San Francisco vs Chicago NFL match-up 10,000 times.
Our leading predictive analytics model gives the 49ers a 62% chance of winning against the Bears in Week 17 of the NFL season.
49ers vs Bears: Odds
The latest Bet365 betting odds in Australia for Monday's NFL game at Levi's Stadium are shown below:
- Head to Head: 49ers $1.48, Bears $2.75
- Line: 49ers -3.5 ($1.91), Bears +3.5 ($1.91)
- Total (Over/Under 51.5 Points): Over $1.91, Under $1.91
Odds are correct at the time of publication and subject to change.
Looking at the latest head-to-head odds, Bet365 currently has the 49ers at $1.48 and the Bears at $2.75.
The 49ers are listed as 3.5-point favourites against the Bears, with odds of $1.91 available at Bet365.
For the underdog Bears (+3.5) to cover the line, Bet365 offers odds of $1.91.
The over/under for total points scored is set at 51.5 with Bet365, which has odds of $1.91 for the over and $1.91 for the under.
According to Stats Insider's model, the bookmakers have got it right and both the 49ers and the Bears have a 50% chance of covering the line.
The 51.5-point over/under is expected to is also considered an equal 50-50 chance of hitting.
49ers vs Bears: Best Bets
- Head to Head: Chicago at $2.75 with Bet365
- Line: Bears +3.5 at $1.91 with Bet365
- Total Points: Under 51.5 at $1.91 with Bet365
Today's 49ers vs Bears betting tips are based on complex modelling and gambling experience to provide you with the best possible advice around the clock.
While the 49ers have a higher chance of winning the game, betting on the Bears to win is our preferred option due to the 1.7% edge identified when comparing our data-led probabilities to the odds currently available.
Making use of the edges published on Stats Insider is pivotal to being profitable in the long run.
49ers vs Bears: Prediction
Stats Insider's predicted final score for 49ers vs Bears at Levi's Stadium in Week 17 is the 49ers winning 27-24.
This prediction is based on each team's average score following 10,000 game simulations.
Stats Insider provides full betting coverage of the San Francisco vs Chicago game in Week 17, including data-driven predictions and expert tips.
18+. Odds correct at time of publishing and subject to change.49ers vs Bears: TD Scorer Tips
Who will score the first touchdown in 49ers vs Bears? The latest data is in.
According to Stats Insider, San Francisco's Christian McCaffrey is the most likely player to score the first TD in 49ers vs Bears.
McCaffrey has an 18.1% chance of getting in for six first at Levi's Stadium, while the 49ers RB has a 66.0% chance of reaching the end zone at any point in the game.
Scroll down for our complete list of first touchdown scorer and anytime touchdown scorer probabilities.
First Touchdown Scorer Tips
49ers First TD Tips
- Christian McCaffrey: 18.1% probability
- Jauan Jennings: 8.4% probability
- Ricky Pearsall: 5.6% probability
- Jake Tonges: 4.0% probability
- Brian Robinson: 3.2% probability
Bears First TD Tips
- D'Andre Swift: 8.0% probability
- Kyle Monangai: 7.0% probability
- DJ Moore: 6.1% probability
- Colston Loveland: 5.4% probability
- Luther Burden: 5.0% probability
Anytime Touchdown Scorer Tips
49ers Anytime TD Tips
- Christian McCaffrey: 66.0% probability
- Jauan Jennings: 39.3% probability
- Ricky Pearsall: 28.2% probability
- Jake Tonges: 21.1% probability
- Brian Robinson: 17.3% probability
Bears Anytime TD Tips
- D'Andre Swift: 37.9% probability
- Kyle Monangai: 34.2% probability
- DJ Moore: 30.7% probability
- Colston Loveland: 27.6% probability
- Luther Burden: 25.8% probability
49ers-Bears Projected Player Stats
Of the starting quarterbacks, the 49ers' Brock Purdy is projected for 257 passing yards. The Bears' Caleb Williams is expected to throw for 228 yards.
49ers Starting QB
- Brock Purdy: 257 projected passing yards
Bears Starting QB
- Caleb Williams: 228 projected passing yards
49ers Rushing Yards
- Christian McCaffrey: 73 projected yards
- Brian Robinson: 24 projected yards
- Brock Purdy: 17 projected yards
Bears Rushing Yards
- D'Andre Swift: 61 projected yards
- Kyle Monangai: 47 projected yards
- Caleb Williams: 23 projected yards
49ers Receiving Yards
- Jauan Jennings: 60 projected yards
- Christian McCaffrey: 48 projected yards
- Ricky Pearsall: 45 projected yards
- Jake Tonges: 34 projected yards
- Kendrick Bourne: 21 projected yards
Bears Receiving Yards
- Luther Burden: 57 projected yards
- Colston Loveland: 44 projected yards
- DJ Moore: 44 projected yards
- Cole Kmet: 26 projected yards
- Jahdae Walker: 19 projected yards
Our model updates regularly, so bookmark this page for the latest betting predictions before the San Francisco vs Chicago match-up.
As always, see Stats Insider's Best Bets for betting tips for every NFL game, as well as predictions for a wide range of other sports.
49ers vs Bears: Week 17 Essential Details
The NFL Week 17 game between the 49ers and Bears at Levi's Stadium is scheduled to begin at 12:20pm AEDT on Monday.
- Teams: San Francisco 49ers vs Chicago Bears
- Date: Monday 29 December 2025
- Time: 12:20pm AEDT
- Venue: Levi's Stadium
All dates and times in this article are in Australian Eastern Daylight Time (AEDT), unless otherwise noted.
Conclusion
Our San Francisco vs Chicago predictions are the result of 10,000 data-driven simulations of the game, carefully curated by our team of experienced data scientists and analysts. We use the latest in predictive analytics technology and machine learning to ensure our NFL tips are accurate and reliable, giving you the confidence to make informed decisions.
If you choose to use our predictions for betting purposes, it's crucial to gamble responsibly and know when to stop. For free and confidential support, call 1800 858 858 or visit gamblinghelponline.org.au.
More on NFL
Stats Insider is your go-to source for betting on the NFL in Australia, with the latest NFL betting news, predictions for every NFL game, and Super Bowl odds for the NFL.
